By Victor Sierpina:"Doc, I just feel tired all the time.” This is the kind of vague complaint, along with dizziness, that challenges every physician. Such patients often show up on a Friday afternoon or mention the fatigue at the end of a visit for other matters. The issue is so common, yet complex, that up to 40 percent of those suffering from chronic fatigue may never receive a specific diagnosis. If you suffer from persistent and severe fatigue, be sure to schedule a visit with your physician to address this problem and to provide plenty of time for him or her to evaluate it with you. At the end of the work-up, what if no specific cause can be identified? What if you are in that 40 percent of mystery fatigue patients? In my experience there are some key issues and common factors that need to be addressed along with some helpful remedies. Here are some examples of these: Consider your sleep habits, getting a good night’s rest along with refreshing naps during the day may solve the problem; Rule out depression; Increase your exercise, especially earlier in the day; If you are overweight, shed some pounds; Consider your diet; Manage stress and consider taking supplements.