OSN SuperSite Breaking News, May 9, 2007 FORT LAUDERDALE, Fla. - A topical chelation therapy was effective in reducing excess intraocular metals that are known to contribute to the formation of diabetic cataracts, according to a poster presentation at the Association for Research in Vision and Ophthalmology meeting here. Naseem H. Ansari, PhD, and colleagues at University of Texas Medical Branch described measures to reduce excess metals and treat or prevent diabetic cataract in a rat model. Research has determined that transition metal ions play a role in generating reactive oxygen species, which increase oxidative stress and cause pathologies such as diabetic cataract, the study authors said.